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Liver failure causes and treatments

What is liver failure?


Liver failure
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Liver failure is a disorder of the liver function responsible for many critical physiological processes in the body and with its loss, the body is significantly damaged.


The term liver disease is broad, as it includes all problems that cause the liver to lose its ability to complete its physiological function after 75% of its tissues are affected, as the liver can compensate for damaged tissues, which distinguishes it from other organs of the body.


The liver is the largest solid organ in the human body. It feeds the hepatic artery, transporting oxygenated blood from the heart and portal vein, and transporting nutrients from the intestines and spleen, as scientists considered it one of the glands for its manufacture and secretion of bile.


Causes of liver failure.


Liver failure is associated with some factors, including:

  • Disruption of blood flow to hepatocytes.

  • Hepatic tissue damage is under the influence of minerals, chemicals, and cell infiltration.

  • Addiction of hepatitis cells as in hepatitis C.

  • Bile outflow obstruction.

  • Accumulation of cholesterol and triglycerides in liver tissues.

  • Alcohol.

  • Excessive dose of some pharmaceutical drugs or vitamins such as vitamin A.

  • Excessive intake of some medicinal herbs.

  • Family history of hereditary liver disease.


Symptoms of liver failure.



 The signs and symptoms of liver failure are as follows:

  • Nausea.

  • Vomiting, especially after eating a high-fat meal.

  • Abdominal pain in the upper right quadrant.

  • Jaundice (yellow pigmentation of the skin due to increased secretion of bile into the bloodstream).

  • Weight loss.

  • general weakness.

  • Ease of bruising, breast enlargement, laziness, and sexual weakness in case of cirrhosis.

How is liver failure diagnosed?


Diagnosis of liver failure depends on some laboratory and radiological tests, including:

  • Laboratory tests for liver function.

  • Computerized tomography or magnetic resonance imaging (MRI) and ultrasound.

  • A tissue biopsy was taken from the liver and examined in the laboratory.

Treatment of liver failure.



Treatment liver failure
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Treatment of kidney failure may include some procedures depending on the causative factor, as follows:


  • Drug therapy against acetaminophen overdose.

  • Supportive treatment for failures caused by viral infection until the virus subsides.

  • Liver transplantation in cases of chronic failure whose diagnosis has been delayed.

  • High temperature in case of cholecystitis caused by gallstones.

How can liver failure be prevented?


  • Drink alcohol in moderation.

  • Avoid risky behaviors such as drug use, tattooing, and unprotected sex.

  • Adherence to hepatitis C vaccinations.  Avoid excessive use of pharmaceutical drugs.

  • Avoid direct contact with the blood or fluids of an infected person with viral hepatitis.

  • Providing the necessary ventilation to reduce the inhalation of detergents scattered in aerosols, pesticides, paint, and other chemicals.

  • Commitment to healthy food.

  • Maintain a healthy weight.

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complications of liver failure.


  • Cerebral edema.

  • Blood clotting disorders.

  • Increased chance of infection.

  • Kidney failure, especially if an overdose of acetaminophen causes liver failure.

What is the course of liver failure disease?


The prognosis of liver failure depends on the causative factor, as the survival rate is 75% after one year of liver transplantation.


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