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What is psoriatic arthritis and what is the psoriatic arthritis treatment ?

An overview of psoriatic arthritis.


psoriatic arthritis
What is psoriatic arthritis and what is the psoriatic arthritis treatment?

Psoriatic arthritis is a type of arthritis that affects some people with psoriasis — a disease in which. 


red spots appear on the skin with silvery scales.  Most people develop psoriasis several years before they are diagnosed with psoriatic arthritis.  But for some, joint problems begin before or at the same time as the skin patches.


Joint torment, solidness, and enlarging are the fundamental signs and side effects of psoriatic joint inflammation. It can influence any piece of the body, including the fingertips and the spine, and can go from gentle to somewhat extreme. For both psoriasis and psoriatic joint pain, patients can vacillate between times of intensification and times of reduction.


There is no cure for psoriatic arthritis, but there are treatments aimed at controlling symptoms and preventing joint damage.  Left untreated, psoriatic arthritis can lead to disability.


Symptoms of psoriatic arthritis.


Psoriatic arthritis and psoriasis are chronic diseases that worsen over time.  However, the patient may experience periods when symptoms improve or temporarily disappear.


Psoriatic arthritis can affect one or both sides of the body.  Psoriatic arthritis and rheumatoid arthritis often have the same signs and symptoms.  Both diseases cause joint pain, swelling, and a feeling of warmth to the touch.


However, psoriatic arthritis is also more likely to cause:

  • Swollen fingers and toes.  Psoriatic arthritis can cause painful swelling in the fingers and toes.

  • Foot pain.  Psoriatic arthritis can also cause pain at the points between the bones, tendons, and ligaments — especially in the back of the heel (Achilles tendinitis) or on the soles of the feet (plantar fasciitis).

  • lower back torment. Certain individuals foster a condition called spondylitis because of psoriatic joint pain. Spondylitis for the most part irritates the joints between the vertebrae of the spine and the joints between the spine and the pelvis (sacroiliitis).

  • Changes in the nails.  Nails can crumble, separate from their base, or have small dents (pits).

  • Eye infection.  Uveitis can cause blurred vision and eye pain and redness.  If uveitis is not treated, it can lead to vision loss.

Causes of psoriatic arthritis.


Psoriatic joint pain happens when the insusceptible framework assaults solid cells and tissues. The resistant reaction causes joint irritation as well as an overproduction of skin cells.


Both hereditary and natural elements seem to assume a part in the insusceptible framework's reaction. Many individuals with psoriatic joint inflammation have a family background of psoriasis or psoriatic joint inflammation. Analysts have found specific hereditary markers that have all the earmarks of being connected to psoriatic joint inflammation.


Physical injury or some environmental trigger — such as a viral or bacterial infection — may cause psoriatic arthritis in people with a genetic predisposition to this condition.


Several factors may increase your risk of developing psoriatic arthritis, including:

  • psoriasis;  Having psoriasis is the single biggest risk factor for psoriatic arthritis.

  • Family medical history.  Many psoriatic arthritis patients have a parent or sibling with the disease.

  • the age.  Although anyone can develop psoriatic arthritis, it most often occurs in adults between the ages of 30 and 55.

Complications of psoriatic arthritis.


A small number of people with psoriatic arthritis develop a condition called atrophic arthritis — a severe form of psoriatic arthritis, which causes pain and disability.  Over time, arthritis destroys the small bones in the hands, especially the fingers, resulting in permanent deformity and disability.


Psoriatic arthritis also increases some people's risk of developing high blood pressure, metabolic syndrome, diabetes, and cardiovascular disease.


Diagnosis of psoriatic arthritis.


During the examination, the doctor may do the following:

  • Checking joints for signs of swelling or painful areas

  • Examining nails for pitting, flaking, and other abnormal signs

  • Apply pressure to the soles of the feet and around the heels to check for painful areas

No single test can affirm a psoriatic joint pain determination. Be that as it may, a few tests can preclude different reasons for joint agony, like rheumatoid joint pain or gout.


Medical Imaging Tests. 


  • X-ray imaging.  This can help detect changes in the joints in cases of psoriatic arthritis, but not in other cases of arthritis.

  • Magnetic resonance imaging (MRI).  This device uses radio waves and a strong magnetic field to create detailed images of the body's hard and soft tissues.  An MRI can be used to check for tendon and ligament problems in the feet and lower back.

laboratory tests. 


  • Rheumatoid factor (RF).  Rheumatoid factor is an antibody that is often found in the blood of people with rheumatoid arthritis but is usually not present in the blood of people with psoriatic arthritis.  This test can help the doctor distinguish between the two conditions.

  • Joint liquid test. A specialist can utilize a needle to extricate a little example of liquid from an impacted joint, regularly the knee. The presence of uric corrosive gems in joint liquid might show gout rather than psoriatic joint inflammation. It's additionally workable for certain individuals to have these two infections simultaneously.

psoriatic arthritis treatment. 



treatment
psoriatic arthritis treatment


There is no cure for psoriatic arthritis, so treatment focuses on controlling the affected joints to prevent motor deficits and joint pain and to control the condition of the skin.  One of the most common treatments is prescription medications called disease-modifying antirheumatic drugs (DMARDs).


Treatment will depend on the severity of the disease and the joints affected.  You may have to try different treatments before you find one that provides relief.


pharmaceutical. 


Prescriptions used to treat psoriatic joint inflammation include:

  • Nonsteroidal calming drugs (NSAIDs) NSAIDs can soothe torment and diminish aggravation in patients with gentle psoriatic joint pain. Over-the-counter sorts incorporate ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve). More grounded types are accessible on a solution. Aftereffects can incorporate stomach disturbance, heart issues, and liver and kidney harm.

  • Conventional disease-modifying antirheumatic drugs (DMARDs) These drugs can slow the progression of psoriatic arthritis and save joints and other tissues from permanent damage.

  • One of the most common is methotrexate (Trexal, Utrexap, others).  Other medications include leflunomide (Arava) and sulfasalazine (Azulfidine).  Side effects can include liver damage, bone marrow suppression, inflammation, and scarring of the lungs (fibrosis).

Biopharmaceuticals.  These drugs are from the class of disease-modifying antirheumatic drugs (DMARDs), which target different immune pathways. These drugs are also known as biological response modifiers.  Examples of biologic drugs include adalimumab (Humera), certolizumab (Simzia), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), ustekinumab (Stelara), secukinumab (Cosentex), ixekizumab (Taltz), golimumab (Atrimacypt), and secukinumab (Taltz).  These medicines can increase the risk of infection.


  • Combined DMARDs tofacitinib (Xeljans) may be used if the patient has not benefited from conventional DMARDs and biologics.  High doses of tofacitinib may increase the risk of lung clots and cancer, as well as serious heart conditions.

  • New medicines are taken by mouth.  Apremilast (Otezla) reduces the activity of an enzyme that controls inflammatory activity within cells.  Apremilast is used for people with mild to moderate psoriatic arthritis who don't want or can't be treated with conventional DMARDs or biologics.  Possible side effects include diarrhea, nausea, and headache.

Treatments. 


Physical and occupational therapy may help relieve pain and make daily tasks easier.  Ask your doctor to advise you about some centers that provide such services.  Massage therapy may also help relieve pain.


Surgical and other procedures. 


  • Steroid injections.  An injection into the affected joint can reduce inflammation.

  • Joint replacement surgery.  Some joints severely affected by psoriatic arthritis can be replaced with artificial joints made of metal and plastic. 

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